anti- Caspase 9 antibody

Descripción

Caspase 9, apoptosis-related cysteine protease(CASP9, synonyms: MCH6, APAF3, APAF-3, ICE-LAP6, CASPASE-9c)is a member of the cysteine-aspartic acid protease(caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. Caspase 9 is processed by APAF1; this step is thought to be one of the earliest in the caspase activation cascade. FNab01295 can recognize the pre-and cleaved-caspase 9.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

caspase 9, apoptosis-related cysteine peptidase

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, IF, IHC, IP, WB, FC

observerd MW

46kd

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:200-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:200; IF: 1:10-1:100

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

CASP9

alias

APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6

uniprot id

https://www.uniprot.org/uniprotkb/P55211

gene id

https://www.ncbi.nlm.nih.gov/gene/842

note

This product is for research use only.

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