CASP1 antibody
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935106861
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name
CASP1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10015
tested applications
ELISA, WB, IHC
Description
CASP1(caspase-1) is also named as IL1BC, IL1BCE and belongs to the peptidase C14A family. It is a cysteine protease that regulates inflammatory processes through its capacity to process and activate the interleukin-1-beta(IL1B), IL18, and IL33 precursor proteins. The active caspase-1 can increase cellular membrane permeability and intracellular calcium levels, which facilitates lysosome exocytosis and release of host antimicrobial factors and microbial products(PMID:21804020). It has 5 isoforms produced by alternative splicing.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | caspase 1 (CASP1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IHC: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 45-47 kDa, 30 kDa, 35 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P29466 |
| Gene ID | 834 |
| Alias | Caspase-1 (CASP-1),Interleukin-1 beta convertase (IL-1BC),Interleukin-1 beta-converting enzyme (ICE, IL-1 beta-converting enzyme),p45,Caspase-1 subunit p20,Caspase-1 subunit p10,CASP1,IL1BC,IL1BCE |
| Background | Antibody anti-CASP1 |
| Status | RUO |
| Note | Mol. Weight 45-47 kDa, 30 kDa, 35 kDa |
Descripción
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