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anti- BCL2 antibody
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935106861
info@markelab.com
Precio
Precio a consultar
Antibody anti-BCL2
proveedor
FineTestreference
FNab00840Tested Applications
ELISA, WB, IP, IHCreactivity
humanstatus
RUOclonality
monoclonalDescripción
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).
Características del producto
category
Primary Antibodies
clonality
monoclonal
reactivity
human
immunogen target
B-cell CLL/lymphoma 2
host
Mouse
isotype
IgG2a
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IP, IHC
observerd MW
26 kDa
purity
≥95% as determined by SDS-PAGE
purification
Protein A+G purification
recommended dilution
WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
BCL2
alias
Bcl-2,PPP1R50,B-Cell CLL/Lymphoma 2
uniprot id
note
This product is for research use only.
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