935106861
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Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Primary Antibodies
monoclonal
human,mouse,rat
BCL2-associated X protein
Mouse
IgG2a
Unconjugated
liquid
ELISA, WB,IHC,IF
21 kDa
≥95% as determined by SDS-PAGE
Protein A+G purification
WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
100µg
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
BAX
BAX,BCL2L4,BCL2 associated X protein,Bcl-2-like protein 4,Bcl2-L-4
This product is for research use only.
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