BACE2 antibody
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935106861
info@markelab.com
name
BACE2 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab10202
tested applications
ELISA, IHC
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Beta-secretase 2 (BACE2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 56 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y5Z0 |
| Gene ID | 25825 |
| Alias | Beta-secretase 2,Aspartic-like protease 56 kDa,Aspartyl protease 1 (ASP1, Asp 1),Beta-site amyloid precursor protein cleaving enzyme 2 (Beta-site APP cleaving enzyme 2),Down region aspartic protease (DRAP),Memapsin-1,Membrane-associated aspartic protease 1,Theta-secretase,BACE2,AEPLC,ALP56,ASP21 |
| Background | Antibody anti-BACE2 |
| Status | RUO |
| Note | Mol. Weight 56 kDa |
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BACE2 antibody
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
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