BACE1 antibody
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Name
BACE1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab10412
Tested Applications
ELISA, WB, IHC
Description
Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | beta-site APP-cleaving enzyme 1 (BACE1) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 50-55 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P56817 |
| Gene ID | 23621 |
| Alias | Beta-secretase 1,Aspartyl protease 2 (ASP2, Asp 2),Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1),Memapsin-2,Membrane-associated aspartic protease 2,BACE1,BACE,KIAA1149 |
| Background | Antibody anti-BACE1 |
| Status | RUO |
| Note | Mol. Weight 50-55 kDa |
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