ATP11B antibody
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Description
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules(Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ATPase, class VI, type 11B (ATP11B) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | IHC: 1:20 - 1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 12 kDd |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q9Y2G3 |
| Gene ID | 23200 |
| Alias | Phospholipid-transporting ATPase IF,ATPase IR,ATPase class VI type 11B,P4-ATPase flippase complex alpha subunit ATP11B,ATP11B,ATPIF,ATPIR,KIAA0956 |
| Background | Antibody anti-ATP11B |
| Status | RUO |
| Note | Mol. Weight 12 kDa |
Descripción
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