MAP3K5 antibody
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Description
ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species(ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase(JNK) and p38.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | mitogen-activated protein kinase kinase kinase 5 (MAP3K5) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:100-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 155 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q99683 |
| Gene ID | 4217 |
| Alias | Mitogen-activated protein kinase kinase kinase 5,Apoptosis signal-regulating kinase 1 (ASK-1),MAPK/ERK kinase kinase 5 (MEK kinase 5, MEKK 5),MAP3K5,ASK1,MAPKKK5,MEKK5 |
| Background | Antibody anti-MAP3K5 |
| Status | RUO |
| Note | Mol. Weight 155 kDa |
Descripción
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ASK1(Apoptosis signal-regulating kinase 1) is also named as MAP3K5, MAPKKK5, MEKK5 and belongs to the MAP kinase kinase kinase subfamily. It is an evolutionarily conserved mitogen activated protein 3-kinase that activates both Jnk and p38 mitogen-activated protein kinases. ASK1 is is activated in response to various cytotoxic stresses including TNF, Fas and reactive oxygen species(ROS) such as H2O2, and activates c-Jun NH 2-terminal kinase(JNK) and p38.
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