anti- APOL4 antibody
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Precio
Precio a consultar
Antibody anti-APOL4
proveedor
FineTestreference
FNab00505Tested Applications
ELISA, IP, WBreactivity
mouse,humanstatus
RUOclonality
polyclonalDescripción
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver(By similarity).
Background
Apolipoprotein L4 (APOL4) is a lesser-studied member of the Apolipoprotein L family and is thought to participate in lipid transport, cellular signaling, and immune modulation. APOL4 is expressed in multiple tissues, including the brain, liver, and immune cells, and localizes to intracellular compartments such as the endoplasmic reticulum and lipid membranes. Like other APOL family members, APOL4 is believed to influence cellular lipid homeostasis, lipid transport pathways, and apoptosis regulation. Its expression is regulated by inflammatory cytokines, suggesting a role in innate immunity and responses to cellular stress. Although the specific biological functions of APOL4 remain unclear, studies indicate that it may contribute to processes such as membrane trafficking, lipid metabolism, and host defense mechanisms against pathogens. Dysregulation of APOL4 expression has been observed in various pathological conditions, including cancers and neurodegenerative diseases, implicating its involvement in cellular survival and disease progression. Further research is needed to fully elucidate APOL4’s functional roles and its potential as a biomarker or therapeutic target in lipid metabolism disorders, immune regulation, and cancer biology.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
mouse,human
immunogen target
apolipoprotein L, 4
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, IP, WB
observerd MW
50-52 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
or code
APOL4
alias
APOLIV,Apolipoprotein L-IV,Apolipoprotein L 4,APOL-IV,Apolipoprotein L4
uniprot id
note
This product is for research use only.
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