ANXA1 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
ANXA1 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab10836
Tested Applications
ELISA, WB, IHC, IF
Description
ANXA1, also named as ANX1, LPC1 and p35, belongs to the annexin family. It is a member of the annexin family of Ca2+-binding and phospholipidbinding proteins, and it is particularly abundant in various populations of peripheral blood leukocytes. ANXA1 regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. ANXA1 is a pleiotrophic protein produced by many cell types including peripheral blood leucocytes. The antibody is specific to ANXA1.
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | annexin A1 (ANXA1) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 1F7 |
| Observed MW | 38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | protein A+G purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P04083 |
| Gene ID | 301 |
| Alias | Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9 |
| Background | Antibody anti-ANXA1 |
| Status | RUO |
| Note | Mol. Weight 38 kDa |
Background
ANXA1 is a calcium-dependent phospholipid-binding protein that plays a critical role in anti-inflammatory responses and cell signaling. It regulates the resolution of inflammation by inhibiting the release of pro-inflammatory mediators and modulating the activity of phospholipase A2 (PLA2). ANXA1 also influences cellular processes such as apoptosis, phagocytosis, and membrane repair. It is expressed in various tissues, including immune cells like neutrophils and macrophages, where it supports immune suppression and tissue repair. Dysregulation of ANXA1 has been implicated in cancer progression, where it can act as either a tumor suppressor or promoter depending on the context. Its anti-inflammatory and apoptotic regulatory properties highlight its therapeutic potential in inflammatory diseases, autoimmune disorders, and cancer.
Productos relacionados
Annexin A1 (ANXA1) Antibody
ANXA1 Antibody is a Rabbit Polyclonal antibody against ANXA1. This gene encodes a membrane-localized protein that binds …
Ver producto
Annexin A1 (ANXA1) Antibody
Annexin I belongs to a family of Ca (2+)-dependent phospholipid binding proteins which have a molecular weight of approx…
Ver producto
Annexin A1 (ANXA1) Antibody
Rabbit polyclonal antibody against ANXA1 protein. Immunogen region is N-terminal.…
Ver producto