ANKRD54 antibody

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935106861
info@markelab.com
name
ANKRD54 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00417
tested applications
ELISA, WB, IHC
Description
Plays an important role in regulating intracellular signaling events associated with erythroid terminal differentiation.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | ankyrin repeat domain 54 (ANKRD54) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | WB: 1:500-1:5000; IHC: 1:20-1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 35 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
UniProt ID | Q6NXT1 |
Gene ID | 129138 |
Alias | ANKRD54,LIAR |
Background | Antibody anti-ANKRD54 |
Status | RUO |
Note | Mol. Weight 35 kDa |
Descripción
ANKRD54 is a protein involved in hematopoiesis and the regulation of erythroid differentiation. It acts as a scaffold protein that interacts with signaling molecules and transcription factors to control red blood cell development and maturation. ANKRD54 is essential for the proper regulation of gene expression in hematopoietic progenitors, influencing processes such as cell survival, proliferation, and differentiation. Mutations or dysregulation of ANKRD54 have been linked to hematopoietic disorders, including anemia and other blood-related abnormalities. Its function in erythroid lineage specification highlights its importance in maintaining the integrity of the blood system and supporting normal hematopoiesis.
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