ANKRD53 antibody
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935106861
info@markelab.com
name
ANKRD53 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00416
tested applications
ELISA, WB, IHC
Description
Required for normal progression through mitosis. Involved in chromosome alignment and cytokinesis via regulation of microtubules polymerization.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ankyrin repeat domain 53 (ANKRD53) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:5000; IF: 1:50-1:500; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8N9V6 |
| Gene ID | 79998 |
| Alias | ANKRD53 |
| Background | Antibody anti-ANKRD53 |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
Descripción
ANKRD53 is a protein containing multiple ankyrin repeat domains, allowing it to mediate protein-protein interactions that regulate various cellular processes. While the exact biological function of ANKRD53 remains unclear, it is believed to be involved in transcriptional regulation and signaling pathways that control cell growth and differentiation. Its expression may be tissue-specific, suggesting specialized roles in certain developmental or stress-related processes. Emerging evidence links ANKRD53 to cellular adaptation mechanisms under metabolic or environmental stress. Dysregulation of ANKRD53 may impact critical pathways, contributing to conditions such as cancer or metabolic disorders.
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