AHSA1 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
AHSA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00232
tested applications
ELISA, IHC, IF, WB, IP
Description
Cochaperone that stimulates HSP90 ATPase activity(By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | AHA1, activator of heat shock 90kDa protein ATPase homolog 1(yeast) (AHSA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200; IP: 1:200-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 38 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, IHC, IF, WB, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95433 |
| Gene ID | 10598 |
| Alias | AHA1, C14orf3, hAha1, p38 |
| Background | Antibody anti-AHSA1 |
| Status | RUO |
| Note | Mol. Weight 38 kDa |
Descripción
Activator of 90 kDa Heat Shock Protein ATPase Homolog 1 (AHSA1) is a co-chaperone protein that enhances the ATPase activity of Hsp90, a molecular chaperone essential for the proper folding, stability, and function of numerous client proteins, including kinases, receptors, and transcription factors. AHSA1 facilitates the Hsp90 chaperone cycle, ensuring efficient protein maturation and stress response. Overexpression of AHSA1 has been linked to cancer, as it enhances the stability of oncogenic client proteins required for tumor progression and survival. AHSA1 is a promising target for cancer therapies aimed at disrupting Hsp90 function. Beyond cancer, AHSA1 also plays a role in protein quality control and cellular stress responses, contributing to proteostasis under normal and pathological conditions.
Related Products
AHSA1 antibody
Cochaperone that stimulates HSP90 ATPase activity(By similarity). May affect a step in the endoplasmic reticulum to Golgi trafficking.
Ver Producto
Recombinant Human AHSA1
Ver Producto