anti- AGBL3 antibody

Name: anti- AGBL3 antibody
Brand: FineTest
SKU: FNab00207
Availability: OnlineOnly

Este producto es parte de AGBL-AGBL carboxypeptidase

Pida mas información

935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-AGBL3

proveedor

FineTest

reference

FNab00207

Tested Applications

ELISA, WB, IHC

reactivity

human,mouse,rat

status

RUO

clonality

polyclonal

Descripción

Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy-terminus of tubulin. Isoform 2: Metallocarboxypeptidase that mediates tubulin deglutamylation.

Background

AGBL3 is a less-characterized member of the AGBL family but is thought to perform similar functions in tubulin deglutamylation, influencing microtubule behavior and cytoskeletal dynamics. It is expressed in a range of tissues, with potential roles in neuronal development, axon guidance, and intracellular trafficking. Mutations or altered expression of AGBL3 have been associated with neurological disorders and certain cancers, suggesting its involvement in maintaining cellular and tissue homeostasis. Further research is needed to elucidate its specific roles in health and disease.

Características del producto

clonality

polyclonal

reactivity

human,mouse,rat

immunogen target

ATP/GTP binding protein-like 3

host

Rabbit

isotype

IgG

conjugation

Unconjugated

form

liquid

tested applications

ELISA, WB, IHC

observerd MW

73 kDa

purity

≥95% as determined by SDS-PAGE

purification

Immunogen affinity purified

recommended dilution

WB: 1:200-1:1000; IHC: 1:20-1:200

size 1

100µg

storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)

or code

AGBL3

alias

CCP3

uniprot id

https://www.uniprot.org/uniprotkb/Q8NEM8

gene id

https://www.ncbi.nlm.nih.gov/gene/340351

note

This product is for research use only.

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