AFM antibody
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935106861
info@markelab.com
name
AFM antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00201
tested applications
ELISA, WB, IHC, IP
Description
Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | afamin (AFM) |
| Host | Mouse |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1:200-1:2000; IP: 1:200-1:2000; IHC: 1:20-1:200 |
| Clonality | monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Clone ID | 3C2 |
| Observed MW | 85 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Protein A+G purification |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P43652 |
| Gene ID | 173 |
| Alias | ALB2,ALBA,alpha-albumin,vitamin E-binding protein |
| Background | Antibody anti-AFM |
| Status | RUO |
| Note | Mol. Weight 85 kDa |
Descripción
Afamin (AFM) , also known as alpha-albumin or vitamin E-binding protein, is a member of the albumin protein family. It is primarily produced in the liver and secreted into the bloodstream, where it functions as a carrier protein for vitamin E. Afamin has a high affinity for various forms of vitamin E, including alpha-tocopherol and gamma-tocopherol. Afamin binds to vitamin E molecules, protecting them from degradation and facilitating their transport to cells throughout the body. Vitamin E is an important antioxidant that helps protect cells from damage caused by free radicals. Afamin may also have additional biological functions, such as inflammation, lipid metabolism, and insulin resistance. However, the full scope of its functions is still being investigated. Afamin levels in the blood have been associated with various health conditions. For example, lower levels of afamin have been observed in individuals with metabolic syndrome, diabetes, and cardiovascular disease. Additionally, afamin levels may be influenced by factors such as age, sex, and hormonal status.
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AFM antibody
Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.
Ver ProductoAFM antibody
Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.
Ver Producto