AFM antibody

Este producto es parte de AFM - Afamin
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935106861
info@markelab.com
name
AFM antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00200
tested applications
ELISA, WB,IP

Description

Vitamin E binding protein. May transport vitamin E in body fluids under conditions where the lipoprotein system is not sufficient. May be involved in the regulation and transport of vitamin E at the blood-brain barrier.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
afamin (AFM)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 1:1000-1:10000; IP: 1:1000-1:10000
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
70 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB,IP
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
UniProt ID
P43652
Gene ID
173
Alias
ALB2,ALBA,alpha-albumin,vitamin E-binding protein
Background
Antibody anti-AFM
Status
RUO
Note
Mol. Weight 70 kDa

Descripción

Afamin (AFM) , also known as alpha-albumin or vitamin E-binding protein, is a member of the albumin protein family. It is primarily produced in the liver and secreted into the bloodstream, where it functions as a carrier protein for vitamin E. Afamin has a high affinity for various forms of vitamin E, including alpha-tocopherol and gamma-tocopherol. Afamin binds to vitamin E molecules, protecting them from degradation and facilitating their transport to cells throughout the body. Vitamin E is an important antioxidant that helps protect cells from damage caused by free radicals. Afamin may also have additional biological functions, such as inflammation, lipid metabolism, and insulin resistance. However, the full scope of its functions is still being investigated. Afamin levels in the blood have been associated with various health conditions. For example, lower levels of afamin have been observed in individuals with metabolic syndrome, diabetes, and cardiovascular disease. Additionally, afamin levels may be influenced by factors such as age, sex, and hormonal status.

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