ADAMDEC1 antibody
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935106861
info@markelab.com
name
ADAMDEC1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00145
tested applications
ELISA, WB, IHC
Description
May play an important role in the control of the immune response and during pregnancy.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | ADAM-like, decysin 1 (ADAMDEC1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:200-1:1000; IHC: 1:20-1:200; IP: 1:50-1:500 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 53 kDa, 44 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O15204 |
| Gene ID | 27299 |
| Alias | ADAM DEC1 |
| Background | Antibody anti-ADAMDEC1 |
| Status | RUO |
| Note | Mol. Weight 53 kDa, 44 kDa |
Descripción
ADAM Like Decysin 1 (ADAMDEC1) is a member of the ADAM (a disintegrin and metalloprotease) family of proteins, which are involved in proteolysis and cell-cell or cell-matrix interactions. Unlike most ADAM proteins, ADAMDEC1 lacks a transmembrane domain, making it a secreted protein. It is primarily expressed in immune-related tissues, such as lymph nodes, the colon, and macrophages, where it is thought to participate in immune response regulation and extracellular matrix remodeling. ADAMDEC1 is involved in degrading extracellular matrix proteins, potentially playing a role in inflammation, tissue remodeling, and immune surveillance. Dysregulation of ADAMDEC1 has been associated with inflammatory conditions and cancer, where altered extracellular matrix remodeling contributes to tumor invasion and metastasis. Emerging research focuses on its role in modulating immune cell activity and its potential as a biomarker or therapeutic target in inflammatory and oncological diseases.
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