ACSL4 antibody
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
ACSL4 antibody
Category
Primary Antibodies
Provider
FineTest
Reference
FNab00108
Tested Applications
ELISA, WB, IHC
Documentos del producto
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | acyl-CoA synthetase long-chain family member 4 (ACSL4) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 79 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O60488 |
| Gene ID | 2182 |
| Alias | ACS4,FACL4,LACS4 MRX63,MRX68 |
| Background | Antibody anti-ACSL4 |
| Status | RUO |
| Note | Mol. Weight 79 kDa |
Background
ACSL4 is an acyl-CoA synthetase with a strong preference for polyunsaturated fatty acids, such as arachidonic and docosahexaenoic acids, converting them into acyl-CoA derivatives for metabolic use. It is highly expressed in the brain, testis, and adrenal glands, where it supports processes requiring specialized lipid metabolism, including the biosynthesis of eicosanoids and membrane lipids. ACSL4 is critical in ferroptosis, a type of programmed cell death triggered by lipid peroxidation, through its role in incorporating polyunsaturated fatty acids into phospholipids. Dysregulation of ACSL4 has been linked to cancer, neurodegenerative diseases, and inflammatory disorders, as it influences processes such as oxidative stress and cellular survival. Its specific role in handling polyunsaturated fatty acids highlights its importance in maintaining cellular lipid balance and preventing oxidative damage under stress conditions.
Productos relacionados
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody
ACSL4 Antibody is a Rabbit Polyclonal antibody against ACSL4. The protein encoded by this gene is an isozyme of the long…
Ver producto
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing…
Ver producto
Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody
Long chain acyl-CoA synthetase (LACS), or long chain fatty acid-CoA ligase (FACL), converts free long chain fatty acids …
Ver producto