anti- ACP1 antibody
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935106861
info@markelab.com
Precio
Precio a consultar
Antibody anti-ACP1
proveedor
FineTestreference
FNab00098Tested Applications
ELISA, WB, IHCreactivity
human,mousestatus
RUOclonality
polyclonalDescripción
The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene.
Background
Acid phosphatases (ACP) are a group of enzymes that catalyze the hydrolysis of phosphate ester bonds under acidic conditions, resulting in the release of inorganic phosphate from organic molecules. These enzymes are characterized by their ability to function optimally at low pH levels. There are multiple forms of acid phosphatase, often denoted as ACP1, ACP2, ACP3, ACP4, and ACP5. Each isoform may have distinct tissue distribution, substrate specificity, and physiological roles. ACP1. It is found in various tissues and body fluids, including red blood cells, bone, prostate gland, and semen. It is a biomarker for poor prognosis in prostate cancer has been linked to bad clinical prognosis. ACP1 (Low Molecular Weight Phosphotyrosine Phosphatase) is widely expressed in various tissues and is nvolved in the dephosphorylation of phosphotyrosine residues on proteins, modulating signal transduction pathways and cell proliferation.
Características del producto
category
Primary Antibodies
clonality
polyclonal
reactivity
human,mouse
immunogen target
acid phosphatase 1, soluble
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
liquid
tested applications
ELISA, WB, IHC
observerd MW
18 kDa
purity
≥95% as determined by SDS-PAGE
purification
Immunogen affinity purified
recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
size 1
100µg
storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
or code
ACP1
alias
HAAP,LMW-PTP,LMWPTP
uniprot id
note
This product is for research use only.
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