ACADS antibody

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Description
This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.
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Product specifications
Category | Primary Antibodies |
Immunogen Target | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (ACADS) |
Host | Rabbit |
Reactivity | Human, Mouse, Rat |
Recommended Dilution | WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200 |
Clonality | polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Observed MW | 44 kDa |
Purity | ≥95% as determined by SDS-PAGE |
Purification | Immunogen affinity purified |
Size 1 | 100µg |
Form | liquid |
Tested Applications | ELISA, WB, IHC, IF |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.) |
UniProt ID | P16219 |
Gene ID | 35 |
Alias | acyl-CoA dehydrogenase C-2 to C-3 short chain,ACAD3,SCAD,Butyryl-CoA Dehydrogenase |
Background | Antibody anti-ACADS |
Status | RUO |
Note | Mol. Weight 44 kDa |
Descripción
The ACADS gene encodes the enzyme acyl-CoA dehydrogenase short chain, a tetrameric mitochondrial flavoprotein involved in the initial step of the mitochondrial fatty acid beta-oxidation pathway. This enzyme belongs to the acyl-CoA dehydrogenase family and is crucial for metabolizing short-chain fatty acids. Mutations in the ACADS gene have been linked to short-chain acyl-CoA dehydrogenase (SCAD) deficiency, a metabolic disorder. Alternative splicing of this gene produces two variants encoding different isoforms of the enzyme.
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This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.
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