ACADS antibody

Este producto es parte de ACADS - Acyl-CoA Dehydrogenase, Short Chain
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935106861
info@markelab.com
name
ACADS antibody
category
Primary Antibodies
provider
FineTest
reference
FNab00066
tested applications
ELISA, WB, IHC, IF

Description

This gene encodes a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with short-chain acyl-CoA dehydrogenase (SCAD) deficiency. Alternative splicing results in two variants which encode different isoforms.

Documents del producto

Instrucciones
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Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain (ACADS)
Host
Rabbit
Reactivity
Human, Mouse, Rat
Recommended Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200
Clonality
polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
44 kDa
Purity
≥95% as determined by SDS-PAGE
Purification
Immunogen affinity purified
Size 1
100µg
Form
liquid
Tested Applications
ELISA, WB, IHC, IF
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
UniProt ID
P16219
Gene ID
35
Alias
acyl-CoA dehydrogenase C-2 to C-3 short chain,ACAD3,SCAD,Butyryl-CoA Dehydrogenase
Background
Antibody anti-ACADS
Status
RUO
Note
Mol. Weight 44 kDa

Descripción

The ACADS gene encodes the enzyme acyl-CoA dehydrogenase short chain, a tetrameric mitochondrial flavoprotein involved in the initial step of the mitochondrial fatty acid beta-oxidation pathway. This enzyme belongs to the acyl-CoA dehydrogenase family and is crucial for metabolizing short-chain fatty acids. Mutations in the ACADS gene have been linked to short-chain acyl-CoA dehydrogenase (SCAD) deficiency, a metabolic disorder. Alternative splicing of this gene produces two variants encoding different isoforms of the enzyme.

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