Annexin A7 (ANXA7) Antibody Pair
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935106861
info@markelab.com
Precio
1027€ (5 × 96 tests)
Antibody Pair for ANXA7
proveedor
Abbexareference
abx370902Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
This product is currently in development. The lead time for this product may be several months. Please contact us at
Background
ANXA7 is a calcium- and GTP-dependent membrane-binding protein that plays a key role in exocytosis, membrane repair, and cell signaling. It acts as a calcium sensor, facilitating the fusion of vesicles with the plasma membrane, particularly in processes such as neurotransmitter release and hormone secretion. ANXA7 is expressed in the brain, heart, and other tissues, where it contributes to cellular calcium homeostasis and cell survival mechanisms. Mutations or dysregulation of ANXA7 have been associated with neurodegenerative diseases, such as Parkinson's disease, and cancers, where it can act as a tumor suppressor by regulating cell proliferation and apoptosis. Its roles in membrane dynamics and calcium-dependent signaling underscore its importance in cellular communication and homeostasis.
Características del producto
category
Antibody Pairs
reactivity
Human
immunogen target
Annexin A7 (ANXA7)
form
Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody) Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.
tested applications
ELISA
size 1
5 × 96 tests
size 2
10 × 96 tests
recommended dilution
Dilute the Capture Antibody 125-fold with Coating Buffer. Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent. Optimal dilutions/concentrations should be determined by the end user.
buffer
The Capture and Detection Antibody both contain 0.1% sodium azide.
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ANXA7
dry ice
No
availability
Please enquire.
alias
ANXA7,ANX7,SNX
uniprot id
note
This antibody pair contains ( 5 x 96 det): Detection: 50 µg Capture: 200 µg Standard: 2 µg This product is for research use only.
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