Annexin A7 (ANXA7) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
ANXA7 Antibody is a Rabbit Polyclonal against ANXA7.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A7 (ANXA7) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/500 - 1/5000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P20073 |
| Gene ID | 310 |
| Alias | ANXA7,ANX7,SNX |
| Background | Antibody anti-ANXA7 |
| Status | RUO |
Descripción
ANXA7 is a calcium- and GTP-dependent membrane-binding protein that plays a key role in exocytosis, membrane repair, and cell signaling. It acts as a calcium sensor, facilitating the fusion of vesicles with the plasma membrane, particularly in processes such as neurotransmitter release and hormone secretion. ANXA7 is expressed in the brain, heart, and other tissues, where it contributes to cellular calcium homeostasis and cell survival mechanisms. Mutations or dysregulation of ANXA7 have been associated with neurodegenerative diseases, such as Parkinson's disease, and cancers, where it can act as a tumor suppressor by regulating cell proliferation and apoptosis. Its roles in membrane dynamics and calcium-dependent signaling underscore its importance in cellular communication and homeostasis.
Related Products
anti- Annexin A2 antibody
Annexin A2(ANXA2), also named Annexin-2 or Lipocortin II, is a Ca2+ binding protein that is up-regulated in virally transformed cell lines and human tumors. This calcium-regulated membrane-binding protein, whose affinity for calcium is greatly enhanced by anionic phospholipids, may cross-link plasma membrane phospholipids with actin and the cytoskeleton and be involved with exocytosis. Heat-stress response may also involve Annexin-2.
Ver Producto
anti- Annexin VII antibody
Annexin A7(Anx7) belongs to a ubiquitous and relatively abundant family of Ca2+-dependent membrane-binding proteins, which are thought to be involved in multiple aspects of cell biology including membrane trafficking, mediation of cell-matrix interactions and membrane organization within cells. Anx7, migrated as a 50 kDa protein in SDS-PAGE, has been proposed to function in the fusion of vesicles, acting as a Ca++ channel and as Ca++-activated GTPase, thus inducing Ca++ /GTP-dependent secretory events.
Ver Producto