Annexin A5 (ANXA5) Antibody
806€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Annexin A5 (ANXA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx171253
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A5 (ANXA5) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ANXA5,ANX5,ENX2,PP4 |
| Background | Antibody anti-ANXA5 |
| Status | RUO |
Descripción
ANXA5 is a well-known calcium- and phospholipid-binding protein involved in apoptosis, membrane repair, and anti-inflammatory processes. It binds to phosphatidylserine (PS), a phospholipid exposed on the outer leaflet of apoptotic cells, making ANXA5 a widely used marker for apoptosis detection. ANXA5 regulates coagulation and fibrinolysis by preventing the assembly of coagulation complexes on cell membranes, contributing to antithrombotic activity. It is expressed in various tissues, including the placenta, where it plays roles in trophoblast function and pregnancy maintenance. Dysregulation of ANXA5 has been associated with autoimmune diseases, recurrent pregnancy loss, and cancers. Its apoptotic and anticoagulant properties make it a key protein in cellular homeostasis and disease pathology.
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