Annexin A1 (ANXA1) Antibody
364€ (100 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Annexin A1 (ANXA1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018325
tested applications
ELISA, WB, IHC
Description
ANXA1 Antibody is a Mouse Monoclonal antibody against ANXA1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Annexin A1 (ANXA1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein A chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NM_000700 |
| Alias | Annexin I,Annexin-1,Calpactin II,Calpactin-2,Chromobindin-9 |
| Background | Antibody anti-ANXA1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
ANXA1 is a calcium-dependent phospholipid-binding protein that plays a critical role in anti-inflammatory responses and cell signaling. It regulates the resolution of inflammation by inhibiting the release of pro-inflammatory mediators and modulating the activity of phospholipase A2 (PLA2). ANXA1 also influences cellular processes such as apoptosis, phagocytosis, and membrane repair. It is expressed in various tissues, including immune cells like neutrophils and macrophages, where it supports immune suppression and tissue repair. Dysregulation of ANXA1 has been implicated in cancer progression, where it can act as either a tumor suppressor or promoter depending on the context. Its anti-inflammatory and apoptotic regulatory properties highlight its therapeutic potential in inflammatory diseases, autoimmune disorders, and cancer.
Related Products
Human ANXA1 (Annexin A1) ELISA Kit
Ver Producto
Mouse ANXA1 (Annexin A1) ELISA Kit
Ver Producto
ANXA1 antibody
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti- inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors.
Ver Producto