Ankyrin Repeat Domain Protein 1 (ANKRD1) Antibody
884€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Ankyrin Repeat Domain Protein 1 (ANKRD1) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx171244
Tested Applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Ankyrin Repeat Domain Protein 1 (ANKRD1) |
| Host | Mouse |
| Reactivity | Rat |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ALRP,C-193,CARP,CVARP |
| Background | Antibody anti-ANKRD1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANKRD1, also known as Cardiac Ankyrin Repeat Protein (CARP), is a transcriptional regulator predominantly expressed in cardiac and skeletal muscles. It localizes to the nucleus and sarcomere, where it interacts with structural proteins like titin and myopalladin. ANKRD1 functions as a stress response protein, upregulated during mechanical stress, injury, and pathological remodeling of the heart. It regulates gene expression through its interaction with transcription factors and participates in processes such as cardiomyocyte differentiation, sarcomeric assembly, and cellular mechanosensing. Mutations or dysregulation of ANKRD1 are associated with dilated cardiomyopathy (DCM) and hypertrophic cardiomyopathy (HCM), where it contributes to altered heart function and structure. ANKRD1 also plays a role in fibrosis, angiogenesis, and cellular signaling pathways activated during heart failure and stress adaptation, making it a potential biomarker for cardiac disorders.
Productos relacionados
Ankyrin Repeat Domain 1 (ANKRD1) Antibody
ANKRD1 Antibody is a Rabbit Polyclonal antibody against ANKRD1. The protein encoded by this gene is localized to the nuc…
Ver producto
Ankyrin Repeat Domain 1 (ANKRD1) Antibody
Rabbit polyclonal antibody against ANKRD1 protein. Immunogen region is C-terminal.…
Ver producto Ankyrin Repeat Domain 1 (ANKRD1) Antibody
Rabbit Polyclonal against the ANKRD1 protein.…
Ver producto