Angiopoietin 2 (ANGPT2) Antibody

Background

Angiogenin 2 (ANG2), also known as Angiopoietin 2 (ANGPT2), plays a role in facilitating ribonuclease activity and is involved in various cellular processes, including cardiac muscle cell development, responses to glucose stimulus, and the positive regulation of protein phosphorylation. It exhibits a strong binding affinity to placental ribonuclease inhibitor but possesses very low ribonuclease activity itself. ANG2 is notably potent in promoting angiogenesis, contributing to the vascularization of both normal and malignant tissues. One of its significant functions is the inhibition of protein synthesis through the specific hydrolysis of cellular transfer RNAs (tRNAs). It is recognized by several aliases, including ANG2, Angiopoietin 2, ANG-2, ANGPT2, and AGPT2.

Background

La Angiogenina 2 (ANG2), también conocida como angiopoyetina 2 (ANGPT2), desempeña un papel en la facilitación de la actividad de la ribonucleasa y participa en diversos procesos celulares, incluido el desarrollo de las células del músculo cardíaco, las respuestas al estímulo de la glucosa y la regulación positiva de la fosforilación de proteínas. Muestra una fuerte afinidad de unión al inhibidor de la ribonucleasa placentaria, pero posee una actividad de ribonucleasa muy baja. ANG2 es notablemente potente para promover la angiogénesis, contribuyendo a la vascularización de tejidos tanto normales como malignos. Una de sus funciones importantes es la inhibición de la síntesis de proteínas mediante la hidrólisis específica de los ARN de transferencia celular (ARNt). Se reconoce por varios alias, incluidos ANG2, Angiopoyetin 2, ANG-2, ANGPT2 y AGPT2.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Angiopoietin 2 (ANGPT2)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC

purity

> 95%

purification

Purified by Protein G.

buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.

size 1

20 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

ANGPT2

dry ice

availability

Shipped within 5-10 working days.

alias

AGPT2,ANG2,LMPHM10

uniprot id

https://www.uniprot.org/uniprotkb/O15123

gene id

https://www.ncbi.nlm.nih.gov/gene/285

NCBI accession

NP_001112359.1, NM_001118887.1

note

This product is for research use only.

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proveedor

FineTest

reference

ER0177

reactivity

rat

status

RUO

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