Angiogenic Factor With G Patch And FHA Domains 1 (AGGF1) Antibody

Background

AGGF1, which stands for Angiogenic Factor with G-patch and FHA domains 1, is a protein that plays a role in angiogenesis, the process of forming new blood vessels from existing ones. AGGF1 is involved in the regulation of endothelial cell proliferation and migration, which are essential steps in angiogenesis.AGGF1 is classified as an angiogenic factor, meaning it promotes the growth and development of blood vessels. The G-patch domain is a conserved motif found in a variety of RNA-binding proteins. Proteins containing G-patch domains are implicated in RNA metabolism, including pre-mRNA splicing, mRNA processing, and RNA export. While the specific role of the G-patch domain in AGGF1 is not fully understood, it suggests a potential involvement in RNA-related processes or interactions. The FHA (Forkhead-associated) domain is a protein module involved in protein-protein interactions and phosphorylation-dependent signaling pathways. FHA domains can bind to phosphorylated serine or threonine residues on target proteins, thereby mediating protein-protein interactions and signaling events. In the context of AGGF1, the FHA domain may participate in protein-protein interactions that regulate its function in angiogenesis.