Amyloid Precursor Protein Antibody

Este producto es parte de APP - Beta-Amyloid Precursor Protein
Product Graph
1118€ (100 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Amyloid Precursor Protein Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx022543
tested applications
WB

Description

Amyloid Precursor Protein Antibody is a Rabbit polyclonal antibody for neuroscience against Amyloid Precursor Protein.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Amyloid Precursor Protein
Host
Rabbit
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by affinity chromatography.
Size 1
100 µg
Form
Liquid
Tested Applications
WB
Buffer
Buffer contains NaN3 as a preservative.
Availability
Shipped within 10-20 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
Background
Antibody anti-APP
Status
RUO

Descripción

APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders

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