Beta-Amyloid Precursor Protein (APP) Antibody (FITC)

Este producto es parte de APP - Beta-Amyloid Precursor Protein
Beta-Amyloid Precursor Protein (APP) Antibody (FITC)

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

Antibody anti-APP

proveedor

Abbexa

reference

abx106551

Tested Applications

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Amyloid beta A4 protein Antibody (FITC) is a Rabbit Polyclonal antibody against Amyloid beta A4 protein conjugated to FITC.


Background

APP is a transmembrane glycoprotein widely expressed in the brain and peripheral tissues that plays a critical role in neuronal development, synaptic plasticity, and cell adhesion APP is proteolytically processed by enzymes such as α-secretase, β-secretase, and γ-secretase, leading to the production of various fragments, including the beta-amyloid (Aβ) peptide Abnormal processing of APP and the accumulation of Aβ peptides form amyloid plaques, which are a hallmark of Alzheimer’s disease and contribute to neurotoxicity and neurodegeneration APP also interacts with various proteins to mediate intracellular signaling and cellular responses Mutations in the APP gene are associated with early-onset familial Alzheimer’s disease, highlighting its role in the pathogenesis of neurodegenerative disorders

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Beta-Amyloid Precursor Protein (APP)


host

Rabbit


conjugation

FITC


form

Liquid


purity

> 95%


purification

Purified by Protein G.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.


or code

APP


dry ice

No


availability

Shipped within 5-10 working days.


alias

AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein


NCBI accession

NP_000475.1, NM_000484.3


note

This product is for research use only.


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