Beta-Amyloid Precursor Protein (APP) Antibody
proveedor
Abbexareference
abx110377Tested Applications
ELISA, WB, IHC, IF/ICCreactivity
Human, Mousestatus
RUOclonality
PolyclonalDescripción
Amyloid beta A4 protein A Antibody is a Rabbit Polyclonal antibody against Amyloid beta A4 protein A.
Background
Amyloid precursor protein (APP) is a highly conserved protein. Amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are homologous of APP. APLP1 was the first identified homologue , while APLP2, was later recognized as another homologue of APP . These three proteins share significant sequence similarity and possess conserved domain structures. APLP1, a type I transmembrane protein, plays a crucial role in synaptic adhesion and synaptogenesis. Is actively involved in the formation of protein-protein complexes that serve as bridges between closely adjacent cells, facilitating cell-cell interactions and communication
Background
La proteína precursora de amiloide (APP) es una proteína altamente conservada. La proteína 1 similar al precursor de amiloide (APLP1) y la proteína 2 similar al precursor de amiloide (APLP2) son homólogas de APP. APLP1 fue el primer homólogo identificado, mientras que APLP2 fue reconocido más tarde como otro homólogo de APP. Estas tres proteínas comparten una similitud de secuencia significativa y poseen estructuras de dominio conservadas. APLP1, una proteína transmembrana de tipo I, desempeña un papel crucial en la adhesión sináptica y la sinaptogénesis. Participa activamente en la formación de complejos proteína-proteína que sirven como puentes entre células estrechamente adyacentes, facilitando las interacciones y la comunicación entre células.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse
immunogen target
Beta-Amyloid Precursor Protein (APP)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB, IHC, IF/ICC
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
APP
dry ice
No
availability
Shipped within 5-10 working days.
alias
AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein
uniprot id
NCBI accession
NP_000475.1, NM_000484.3
note
This product is for research use only.
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