Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody is a Rabbit polyclonal antibody for the detection of Human Amyloid Beta Precursor Like Protein 2 (APLP2).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Amyloid Beta Precursor Like Protein 2 (APLP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q06481 |
| Gene ID | 334 |
| NCBI Accession | NP_001135748.1 |
| Background | Antibody anti-APLP2 |
| Status | RUO |
Descripción
Related Products
Human APLP2 (Amyloid-like protein 2) ELISA Kit
Ver Producto
APLP2 antibody
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts(By similarity).
Ver Producto
Amyloid Beta Precursor Like Protein 2 (APLP2) Antibody
APLP2 Antibody is a Rabbit Polyclonal antibody against APLP2. This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto