Beta-Amyloid Precursor Protein (APP) Antibody

Pida mas información

935106861

info@markelab.com

Precio

187.5€ (50 µg)

proveedor

Abbexa

reference

abx329471

Tested Applications

ELISA, WB, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

APP Antibody is a Rabbit Polyclonal against APP.

Background

Amyloid precursor protein (APP) is a highly conserved protein. Amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are homologous of APP. APLP1 was the first identified homologue , while APLP2, was later recognized as another homologue of APP . These three proteins share significant sequence similarity and possess conserved domain structures. APLP1, a type I transmembrane protein, plays a crucial role in synaptic adhesion and synaptogenesis. Is actively involved in the formation of protein-protein complexes that serve as bridges between closely adjacent cells, facilitating cell-cell interactions and communication

Background

La proteína precursora de amiloide (APP) es una proteína altamente conservada. La proteína 1 similar al precursor de amiloide (APLP1) y la proteína 2 similar al precursor de amiloide (APLP2) son homólogas de APP. APLP1 fue el primer homólogo identificado, mientras que APLP2 fue reconocido más tarde como otro homólogo de APP. Estas tres proteínas comparten una similitud de secuencia significativa y poseen estructuras de dominio conservadas. APLP1, una proteína transmembrana de tipo I, desempeña un papel crucial en la adhesión sináptica y la sinaptogénesis. Participa activamente en la formación de complejos proteína-proteína que sirven como puentes entre células estrechamente adyacentes, facilitando las interacciones y la comunicación entre células.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Beta-Amyloid Precursor Protein (APP)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB, IHC, IF/ICC

purification

Purified by affinity chromatography.

buffer

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

size 1

50 µg

size 2

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

APP

dry ice

availability

Shipped within 5-10 working days.

alias

AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein

uniprot id

https://www.uniprot.org/uniprotkb/P05067

gene id

https://www.ncbi.nlm.nih.gov/gene/351

note

This product is for research use only.

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proveedor

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reference

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reactivity

rat

status

RUO

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