Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody
195€ (20 µl)
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935106861
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name
Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001587
tested applications
ELISA, WB
Description
APBB1 Antibody is a Rabbit Polyclonal antibody against APBB1. The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Amyloid-Beta A4 Precursor Protein-Binding Family B Member 1 (APBB1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O00213 |
| Gene ID | 322 |
| NCBI Accession | NP_663722.1 |
| Background | Antibody anti-APBB1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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