Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2) Antibody

Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2) Antibody

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935106861

info@markelab.com

Precio

362.5€ (100 µl)

proveedor

Abbexa

reference

abx224467

Tested Applications

ELISA, WB, FCM

reactivity

Human, Rat

status

RUO

clonality

Monoclonal

Descripción

APBA2 Antibody is a Mouse Monoclonal against APBA2.

Background

Amyloid precursor protein (APP) is a highly conserved protein. Amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are homologous of APP. APLP1 was the first identified homologue , while APLP2, was later recognized as another homologue of APP . These three proteins share significant sequence similarity and possess conserved domain structures. APLP1, a type I transmembrane protein, plays a crucial role in synaptic adhesion and synaptogenesis. Is actively involved in the formation of protein-protein complexes that serve as bridges between closely adjacent cells, facilitating cell-cell interactions and communication

Background

La proteína precursora de amiloide (APP) es una proteína altamente conservada. La proteína 1 similar al precursor de amiloide (APLP1) y la proteína 2 similar al precursor de amiloide (APLP2) son homólogas de APP. APLP1 fue el primer homólogo identificado, mientras que APLP2 fue reconocido más tarde como otro homólogo de APP. Estas tres proteínas comparten una similitud de secuencia significativa y poseen estructuras de dominio conservadas. APLP1, una proteína transmembrana de tipo I, desempeña un papel crucial en la adhesión sináptica y la sinaptogénesis. Participa activamente en la formación de complejos proteína-proteína que sirven como puentes entre células estrechamente adyacentes, facilitando las interacciones y la comunicación entre células.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human, Rat


immunogen target

Amyloid-Beta A4 Precursor Protein-Binding Family A Member 2 (APBA2)


host

Mouse


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, WB, FCM


purification

Purified from ascites by Protein G chromatography.


buffer

PBS, containing 0.05% sodium azide.


size 1

100 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

APBA2


dry ice

No


availability

Shipped within 5-10 working days.


alias

APBA2, D15S1518E, HsT16821, LIN-10, MGC:14091, MINT2, X11-BETA, X11L, amyloid beta precursor protein binding family A member 2


note

This product is for research use only.


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