Beta-Amyloid Precursor Protein (APP) Antibody

Beta-Amyloid Precursor Protein (APP) Antibody

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935106861

info@markelab.com

Precio

337.5€ (100 µg)

proveedor

Abbexa

reference

abx037912

Tested Applications

ELISA, IHC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

Rabbit Polyclonal against the Beta-Amyloid Precursor Protein.

Background

Amyloid precursor protein (APP) is a highly conserved protein. Amyloid precursor-like protein 1 (APLP1) and amyloid precursor-like protein 2 (APLP2) are homologous of APP. APLP1 was the first identified homologue , while APLP2, was later recognized as another homologue of APP . These three proteins share significant sequence similarity and possess conserved domain structures. APLP1, a type I transmembrane protein, plays a crucial role in synaptic adhesion and synaptogenesis. Is actively involved in the formation of protein-protein complexes that serve as bridges between closely adjacent cells, facilitating cell-cell interactions and communication

Background

La proteína precursora de amiloide (APP) es una proteína altamente conservada. La proteína 1 similar al precursor de amiloide (APLP1) y la proteína 2 similar al precursor de amiloide (APLP2) son homólogas de APP. APLP1 fue el primer homólogo identificado, mientras que APLP2 fue reconocido más tarde como otro homólogo de APP. Estas tres proteínas comparten una similitud de secuencia significativa y poseen estructuras de dominio conservadas. APLP1, una proteína transmembrana de tipo I, desempeña un papel crucial en la adhesión sináptica y la sinaptogénesis. Participa activamente en la formación de complejos proteína-proteína que sirven como puentes entre células estrechamente adyacentes, facilitando las interacciones y la comunicación entre células.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human, Mouse, Rat


immunogen target

Beta-Amyloid Precursor Protein (APP)


host

Rabbit


conjugation

Unconjugated


form

Lyophilized


tested applications

ELISA, IHC


purification

Purified by antigen affinity column chromatography.


buffer

Prior to lyophilization: 1% BSA and 0.02% NaN3.


size 1

100 µg


storage

Store at -20 °C. Avoid repeated freeze/thaw cycles.


or code

APP


dry ice

No


availability

Shipped within 7-15 working days.


alias

AAA,AD1,PN2,ABPP,APPI,CVAP,ABETA,PN-II,preA4,CTFgamma,alpha-sAPP,Alzheimer disease amyloid protein


note

This product is for research use only.


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