Aminopeptidase N (ANPEP) Antibody
299€ (50 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Aminopeptidase N (ANPEP) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx349852
Tested Applications
ELISA, IF/ICC, FCM
Description
Aminopeptidase N (ANPEP) Antibody is a Recombinant Mouse Monoclonal antibody for the detection of Human ANPEP.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Aminopeptidase N (ANPEP) Immunogen: Recombinant Human ANPEP protein |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | IF/ICC: 1/20 - 1/200, FCM: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC, FCM |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P15144 |
| Gene ID | 290 |
| OMIM | 151530 |
| Alias | APN,AP-M,AP-N,CD13,LAP1,P150,PEPN,Hapn,GP150,Aminopeptidase N,Alanyl aminopeptidase,Microsomal aminopeptidase,Myeloid plasma membrane glycoprotein |
| Background | Antibody anti-ANPEP |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ANPEP, also known as alanyl aminopeptidase or aminopeptidase N (APN), is a key membrane-bound enzyme that plays a significant role in the hydrolysis of peptides. The gene ANPEP encodes this enzyme, which is expressed predominantly on the surface of epithelial cells in the small intestine, kidney, and other tissues, and also in certain immune cells such as monocytes, macrophages, and granulocytes. ANPEP is classified as a zinc metalloprotease, which means that its catalytic activity depends on a zinc ion in its active site. In the small intestine, ANPEP facilitates the final stages of protein digestion by cleaving neutral amino acids from the N-terminus of oligopeptides. Beyond its digestive role, ANPEP also participates in various physiological processes, including antigen processing, angiogenesis, immune response regulation, and the inflammatory response