Aminoadipate Semialdehyde Synthase (AASS) Antibody

Product specifications

Primary Antibodies

Aminoadipate Semialdehyde Synthase (AASS)

Rabbit

Human

ELISA: 1/10000, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified by affinity chromatography.

50 µg

100 µg

Liquid

ELISA, WB

PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

Q9UDR5

10157

LKRSDH,LORSDH,LKR/SDH

Antibody anti-AASS

RUO

Descripción

Alpha-aminoadipic semialdehyde synthase (AASS) is a bifunctional mitochondrial enzyme involved in the lysine degradation pathway. It catalyzes two sequential reactions: the oxidation of lysine to saccharopine via its lysine-ketoglutarate reductase activity and the subsequent conversion of saccharopine to alpha-aminoadipic semialdehyde via saccharopine dehydrogenase activity. This pathway plays a crucial role in amino acid catabolism and the production of acetyl-CoA, linking it to energy metabolism and the tricarboxylic acid (TCA) cycle. AASS is essential for maintaining lysine homeostasis and energy production, particularly under conditions of low glucose availability. Mutations in the AASS gene can lead to hyperlysinemia, a metabolic disorder characterized by elevated lysine levels in the blood and associated neurological symptoms. Emerging studies suggest AASS may also play a regulatory role in mitochondrial function and oxidative stress responses.

Related Products

Aminoadipate Semialdehyde Synthase (AASS) Antibody

Rabbit Polyclonal against the AASS protein.

Ver Producto

Aminoadipate Semialdehyde Synthase (AASS) Antibody

Rabbit Polyclonal against the AASS protein.

Ver Producto

Aminoadipate Semialdehyde Synthase (AASS) Antibody

AASS Antibody is a Rabbit Polyclonal against AASS.

Ver Producto