Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (PerCP)
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Description
Alpha Synuclein Phospho-Ser129 (SNCA pS129) Antibody (PerCP) is a rabbit monoclonal antibody against Alpha Synuclein Phospho-Ser129 (SNCA pS129). Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha Synuclein Phospho-Ser129 (SNCA pS129) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Data | Modification: Phosphorylation // Target Modification: Ser129 |
| Recommended Dilution | WB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PerCP |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 100 µg |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS, pH 7.4, 50% glycerol, 0.09% sodium azide. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P37840 |
| Gene ID | 6622 |
| NCBI Accession | NP_000336.1 |
| OMIM | 163890 |
| Alias | SNCA |
| Background | Antibody anti-aSyn |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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