Alpha-Amylase 1 (AMY1A) Antibody
169€ (20 µl)
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935106861
info@markelab.com
name
Alpha-Amylase 1 (AMY1A) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx320163
tested applications
ELISA, IHC
Description
AMY1A Antibody is a Rabbit Polyclonal against AMY1A.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Alpha-Amylase 1 (AMY1A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04745 |
| Gene ID | 276, 277, 278 |
| Alias | AMY1 |
| Background | Antibody anti-AMY1A |
| Status | RUO |
Descripción
AMY1A, also known as salivary alpha-amylase, is an enzyme responsible for catalyzing the hydrolysis of starch into smaller sugar molecules such as maltose and dextrins. It is primarily produced in the salivary glands and is secreted into the oral cavity, where it initiates the digestion of carbohydrates during chewing. AMY1A plays a key role in the first step of dietary carbohydrate breakdown, facilitating glucose availability for energy production. Variations in AMY1A gene copy number influence enzyme levels, with higher AMY1A expression linked to increased starch digestion efficiency. This variation is thought to have evolved in populations with high-starch diets. AMY1A also functions as a stress biomarker because its production is upregulated in response to sympathetic nervous system activation, making it a marker for acute stress, emotional states, and physical activity. Dysregulation of AMY1A has been associated with conditions such as obesity, metabolic syndrome, and type 2 diabetes, where altered carbohydrate metabolism plays a role in disease progression.
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