Alpha-(1,3)-Fucosyltransferase 4 (FUT4) Antibody
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935106861
info@markelab.com
Precio
275€ (40 µl)
Antibody anti-FUT4
proveedor
Abbexareference
abx227137Tested Applications
IHCreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
Alpha-(1,3)-Fucosyltransferase 4 (FUT4) Antibody is a Rabbit Monoclonal antibody for the detection of CD21.
Background
FUT4 (fucosyltransferase 4) is a crucial enzyme in the glycosylation process, specifically responsible for catalyzing the transfer of fucose, a hexose sugar, to target glycoproteins and glycolipids. This process is essential in forming fucosylated glycans, such as the Lewis antigens. FUT4 belongs to the broader family of fucosyltransferases, enzymes that facilitate the addition of fucose residues to various substrates. These glycosylation modifications are important for many cellular functions, including cell adhesion, signal transduction, immune response, and development. One of the primary roles of FUT4 is in the synthesis of Lewis X antigen (CD15), a fucosylated oligosaccharide that plays a critical role in mediating cell-cell interactions. FUT4 is encoded by the FUT4 gene, which is located on chromosome 11q21-22 in humans. It is expressed in a variety of tissues but is especially prominent in the bone marrow, placenta, and immune cells. The enzyme's activity has been linked to processes such as leukocyte trafficking, inflammation, and tumor metastasis, due to its ability to regulate the presentation of fucosylated antigens on the cell surface.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
Alpha-(1,3)-Fucosyltransferase 4 (FUT4)
host
Rabbit
conjugation
Unconjugated
form
Liquid
tested applications
IHC
purification
Purified from rabbit antiserum by proprietary techniques.
buffer
20 mM Tris-HCl, pH 8.0, containing 20 mg/ml BSA and 0.05% NaN3.
size 1
40 µl
size 2
100 µl
size 3
200 µl
size 4
500 µl
size 5
1 ml
storage
Store at 2-8°C.
or code
FUT4
dry ice
No
availability
Shipped within 5-10 working days.
alias
LeX,CD15,ELFT,FCT3A,FUTIV,SSEA-1,FUC-TIV,Alpha-(1,3)-fucosyltransferase 4,Fucosyltransferase 4,Galactoside 3-L-fucosyltransferase
uniprot id
note
This product is for research use only.
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