alpha-1-Antitrypsin (SERPINA1) Antibody
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935106861
info@markelab.com
Precio
416€ (200 µl)
Antibody anti-SERPINA1
proveedor
Abbexareference
abx432315Tested Applications
P-ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
alpha-1-antitrypsin Antibody is a Goat Polyclonal antibody against alpha-1-antitrypsin.
Background
The SERPINA1 gene, commonly known as alpha-1 antitrypsin (A1AT), encodes a protein that plays a crucial role in protecting tissues from enzymes of inflammatory cells, particularly neutrophil elastase. This gene is part of the serine protease inhibitor (serpin) superfamily and is located on chromosome 14 (14q32.13). Alpha-1 antitrypsin is primarily synthesized in the liver, although it is also produced in smaller quantities by other tissues, including the lungs, intestines, and kidneys. The protein encoded by SERPINA1 is a glycoprotein that circulates in the blood and functions as a major inhibitor of proteases, especially neutrophil elastase, which, if left unchecked, can degrade elastin and other extracellular matrix components, leading to tissue damage.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
alpha-1-Antitrypsin (SERPINA1)
host
Goat
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
P-ELISA, WB
purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
recommended dilution
P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user.
buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
size 1
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
SERPINA1
dry ice
No
availability
Shipped within 5-10 working days.
alias
PI,A1A,AAT; PI1,A1AT,nNIF,PRO2275,alpha1AT,Alpha-1-antitrypsin,Alpha-1 protease inhibitor,Alpha-1-antiproteinase,Serpin A1
NCBI accession
NP_000286.3
note
Concentration: 0.5 mg/ml -
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