Alpha-1-Acid Glycoprotein 2 (ORM2) Antibody Pair

Product specifications

Antibody Pairs

Alpha-1-Acid Glycoprotein 2 (ORM2)

Mouse

Capture: Rabbit  Polyclonal

Detection:  Rabbit  Polyclonal (Biotin)

Sandwich

9.4 ng/ml - 600 ng/ml

Dilute the Capture Antibody 125-fold with Coating Buffer.  Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent.  Optimal dilutions/concentrations should be determined by the end user.

5 × 96 tests

10 × 96 tests

Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody)

Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.

ELISA

The Capture and Detection Antibody both contain 0.1% sodium azide.

Shipped within 5-20 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

AGP2,AGP-B,AGP-B,Orosomucoid 2,OMD 2,Orosomucoid-2

Antibody Pair for ORM2

RUO

This antibody pair contains ( 5 x 96 det):    Detection:  50 µg  Capture:  200 µg  Standard:  5 µg

This product is for research use only.

Descripción

Alpha-1-acid glycoprotein 2 (ORM2), also known as orosomucoid 2, is a major acute-phase protein predominantly produced in the liver and secreted into the bloodstream. ORM2 belongs to the lipocalin family, a group of small proteins characterized by their ability to bind and transport small hydrophobic molecules, including drugs, steroids, and lipids. As an acute-phase reactant, ORM2 levels increase significantly in response to inflammation, infection, trauma, or other physiological stresses, playing a critical role in the systemic inflammatory response.ORM2 is closely related to ORM1 (Alpha-1-acid glycoprotein 1), with both proteins sharing high sequence and structural homology. Together, they constitute the majority of the alpha-1-globulin fraction in human plasma. ORM2 has immunomodulatory functions, influencing immune cell activity, vascular permeability, and interactions between cytokines. Additionally, ORM2 is significant in pharmacology because it binds to various drugs, impacting their bioavailability and pharmacokinetics.

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Human ORM2 (Alpha-1-acid glycoprotein 2) ELISA Kit

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Mouse ORM2 (Orosomucoid 2) ELISA Kit

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ORM2 antibody

ORM2, also named as AGP2 and OMD 2, belongs to the calycin superfamily and Lipocalin family. It functions as transport protein in the blood stream. ORM2 binds various hydrophobic ligands in the interior of its beta-barrel domain. It also binds synthetic drugs and influences their distribution and availability. ORM2 appears to function in modulating the activity of the immune system during the acute-phase reaction. ORM2 is one of the conserved endoplasmic reticulum membrane proteins which regulating lipid homeostasis and protein quality control. This antibody can recognize both ORM1 and ORM2.

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