Alpha-1-Acid Glycoprotein 1 (ORM1) Protein

Background

Alpha-1-Acid Glycoprotein (ORM1), also known as orosomucoid, is an acute-phase plasma protein predominantly synthesized in the liver. ORM1 is a part of the acute-phase response, where its levels in the blood increase in response to inflammation, infection, or injury.It is a 43-44 kDa glycoprotein well known as a one of the major acute phase proteins in humans, rats and many other spices The carbohydrate content represents 45% of the molecular weight attached in the form of five to six highly sialylated complex-type-N-linked glycans.ORM1 has since been studied extensively for its role in immune regulation, drug binding, and inflammation.