Alkaline Phosphatase, Placental Type (ALPP) Antibody

Pida mas información
935106861
info@markelab.com
Precio
292.5€ (80 µl)
Antibody anti-ALPP
proveedor
Abbexareference
abx025392Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Background
Alkaline phosphatase, germ cell type (ALPP) is an enzyme that is predominantly expressed in germ cells, which are the cells that give rise to sperm and eggs. ALPP is also known as germ cell alkaline phosphatase (GCAP).GCAP is a type of alkaline phosphatase that is specifically expressed in germ cells during spermatogenesis and oogenesis. It plays a role in the development and maturation of germ cells, although its exact function in this process is not fully understood. GCAP is sometimes used as a marker for germ cell tumors. These tumors originate from germ cells and can occur in various locations in the body, including the testes, ovaries, and extragonadal sites. Elevated levels of GCAP in the blood or other bodily fluids may indicate the presence of germ cell tumors. GCAP is also used as a marker for identifying the presence of germ cells in certain tissues, such as testicular biopsies or embryonic stem cell cultures, where the presence of germ cells is of interest for research or diagnostic purposes.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
Alkaline Phosphatase, Placental Type (ALPP)
host
Mouse
isotype
IgG1
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
recommended dilution
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS containing 0.09% sodium azide.
size 1
80 µl
size 2
400 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
ALPP
dry ice
No
availability
Shipped within 5-10 working days.
alias
ALPP,PLAP
uniprot id
Quizá le pueda interesar
Human ALPP(Alkaline phosphatase, placental type) ELISA Kit

proveedor
FineTestreference
EH1391reactivity
humanstatus
RUOPrecio a consultar
Ver másAlkaline Phosphatase, Placental Type (ALPP) Antibody

proveedor
Abbexareference
abx006623Tested Applications
WB, IPreactivity
Humanstatus
RUOclonality
PolyclonalALPP Antibody is a Rabbit Polyclonal Antibody against ALPP.
312€ (60 µl)
Ver másAlkaline Phosphatase, Placental Type (ALPP) Antibody

proveedor
Abbexareference
abx011923Tested Applications
ELISA, WB, IHCreactivity
Humanstatus
RUOclonality
MonoclonalThere are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bon...
383.5€ (100 µl)
Ver más