Aldosterone (ALD) CLIA Kit
871€ (96 tests)
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name
Aldosterone (ALD) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx490318
tested applications
CLIA
Description
Aldosterone Chemiluminescent Immunoassay (CLIA) Kit is a Competitive Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma and other biological fluids.
Documents del producto
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Aldosterone (ALD) |
| Reactivity | General |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Competitive |
| Test Range | 7.8 pg/ml - 2000 pg/ml |
| Sensitivity | < 2.93 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | Aldocorten,Aldocortin |
| Background | CLIA Kits ALD |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Aldosterone is a steroid hormone synthesized in the zona glomerulosa of the adrenal cortex and plays a critical role in the regulation of electrolyte balance and blood pressure it acts on mineralocorticoid receptors in the kidneys to increase sodium reabsorption and potassium excretion in the distal tubules and collecting ducts this sodium retention leads to water retention contributing to blood volume and pressure maintenance aldosterone secretion is primarily regulated by the renin-angiotensin-aldosterone system (RAAS) as well as potassium levels and adrenocorticotropic hormone (ACTH) dysregulation of aldosterone can lead to conditions such as primary hyperaldosteronism (Conn's syndrome) characterized by hypertension and hypokalemia and hypoaldosteronism which can result in hyperkalemia and hypotension aldosterone measurement is crucial in diagnosing these conditions with techniques such as ELISA and CLIA commonly used to quantify its levels in plasma research into aldosterone antagonists is ongoing for the treatment of resistant hypertension and heart failure where aldosterone plays a pathological role in promoting fibrosis and vascular dysfunction
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