Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Peptide

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Description
Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) Peptide is a synthetic peptide.
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Product specifications
Category | Proteins and Peptides |
Immunogen Target | Aldo-Keto Reductase Family 1 Member C3 (AKR1C3) |
Host | Synthetic |
Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
Conjugation | Unconjugated |
Observed MW | Sequence Fragment: C-Terminus: CFASHPNYPYSDEY |
Size 1 | 100 µg |
Form | Lyophilized Reconstitute in deionized water. |
Tested Applications | P-ELISA |
Buffer | Prior to lyophilization: Deionized water. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 8644 |
NCBI Accession | NP_003730.4 |
Alias | AKR1C3, DDH1, HSD17B5, KIAA0119, PGFS |
Background | Protein AKR1C3 |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha, 11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding different isoforms have been found for this gene.
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