Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx315195
tested applications
ELISA
Description
ALDH9A1 Antibody (HRP) is a Rabbit Polyclonal against ALDH9A1 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49189 |
| Gene ID | 223 |
| NCBI Accession | NP_000687.3, NM_000696.3, XP_011507596.1, XM_011509294.2 |
| OMIM | 602733 |
| Alias | ALDH9A1,ALDH4,ALDH7,ALDH9 |
| Background | Antibody anti-ALDH9A1 |
| Status | RUO |
Descripción
ALDH9A1 is a cytosolic enzyme that oxidizes γ-aminobutyraldehyde (GABAL) and betaine aldehyde to their respective acids, playing a role in neurotransmitter metabolism and osmolyte synthesis. It is highly expressed in the liver, brain, and kidneys, where it supports the conversion of GABAL to GABA, an important inhibitory neurotransmitter, and the conversion of betaine aldehyde to betaine, a key osmolyte involved in cellular hydration and methylation processes. ALDH9A1’s function is critical for maintaining GABA homeostasis, osmotic balance, and methyl group donation in metabolic pathways. Dysregulation of ALDH9A1 has been associated with neurological disorders, where impaired GABA metabolism can contribute to excitotoxicity and neurodegeneration. ALDH9A1 also protects cells from aldehyde toxicity, as it detoxifies reactive intermediates generated during amino acid and lipid metabolism. Its role in neurotransmitter balance and cellular protection makes it a target for neurological and metabolic disease therapies.
Related Products
Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Antibody
ALDH9A1 belongs to the aldehyde dehydrogenase family of proteins. The protein has a high activity for oxidation of gamma-aminobutyraldehyde and other amino aldehydes. The enzyme catalyzes the dehydrogenation of gamma-aminobutyraldehyde to gamma-aminobutyric acid (GABA). This isozyme is a tetramer of identical 54-kD subunits.
Ver Producto
Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Antibody
ALDH9A1 Antibody is a Rabbit Polyclonal Antibody against ALDH9A1.
Ver Producto
Aldehyde Dehydrogenase 9 Family, Member A1 (ALDH9A1) Antibody
Aldehyde Dehydrogenase 9 Family, Member A1 Antibody is a Rabbit Polyclonal against Aldehyde Dehydrogenase 9 Family, Member A1.
Ver Producto