Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody (FITC)

Este producto es parte de ALDH - Aldehyde dehydrogenase family member
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169€ (20 µg)

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935106861
info@markelab.com
name
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx334639

Description

ALDH3B1 Antibody (FITC) is a Rabbit Polyclonal against ALDH3B1.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetAldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationFITC
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP43353
Gene ID221
AliasALDH3B1,ALDH7,Aldehyde dehydrogenase 7
BackgroundAntibody anti-ALDH3B1
StatusRUO

Descripción

ALDH3B1 is a cytosolic enzyme involved in the detoxification of reactive aldehydes generated from lipid peroxidation and environmental toxins. It is expressed in various tissues, including the liver, kidneys, and lungs, where it plays a protective role against oxidative stress and aldehyde-induced cellular damage. ALDH3B1 contributes to cellular homeostasis by metabolizing toxic aldehydes such as formaldehyde and 4-HNE, reducing protein and DNA adduct formation. Dysregulation of ALDH3B1 has been linked to metabolic and neurodegenerative disorders, where impaired aldehyde detoxification exacerbates oxidative damage. In cancer, ALDH3B1 has been identified as a tumor suppressor in certain contexts, as its activity reduces cellular oxidative stress and inhibits tumor progression. Recent studies suggest its involvement in maintaining redox balance and preventing aldehyde-associated toxicity in tissues exposed to oxidative or environmental stressors.

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