Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody (Biotin)
169€ (20 µg)
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Name
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx334640
Tested Applications
ELISA
Description
ALDH3B1 Antibody (Biotin) is a Rabbit Polyclonal against ALDH3B1.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Immunogen: Recombinant Human Aldehyde dehydrogenase family 3 member B1 protein (168-449AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43353 |
| Gene ID | 221 |
| Alias | ALDH3B1,ALDH7,Aldehyde dehydrogenase 7 |
| Background | Antibody anti-ALDH3B1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
ALDH3B1 is a cytosolic enzyme involved in the detoxification of reactive aldehydes generated from lipid peroxidation and environmental toxins. It is expressed in various tissues, including the liver, kidneys, and lungs, where it plays a protective role against oxidative stress and aldehyde-induced cellular damage. ALDH3B1 contributes to cellular homeostasis by metabolizing toxic aldehydes such as formaldehyde and 4-HNE, reducing protein and DNA adduct formation. Dysregulation of ALDH3B1 has been linked to metabolic and neurodegenerative disorders, where impaired aldehyde detoxification exacerbates oxidative damage. In cancer, ALDH3B1 has been identified as a tumor suppressor in certain contexts, as its activity reduces cellular oxidative stress and inhibits tumor progression. Recent studies suggest its involvement in maintaining redox balance and preventing aldehyde-associated toxicity in tissues exposed to oxidative or environmental stressors.
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