Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
221€ (50 µg)
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935106861
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name
Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx324627
tested applications
ELISA, WB, IHC
Description
ALDH3B1 Antibody is a Rabbit Polyclonal against ALDH3B1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Aldehyde Dehydrogenase 3 Family Member B1 (ALDH3B1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/40000, WB: 1/500 - 1/2000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P43353 |
| Gene ID | 221 |
| Alias | ALDH3B1,ALDH7,Aldehyde dehydrogenase 7 |
| Background | Antibody anti-ALDH3B1 |
| Status | RUO |
Descripción
ALDH3B1 is a cytosolic enzyme involved in the detoxification of reactive aldehydes generated from lipid peroxidation and environmental toxins. It is expressed in various tissues, including the liver, kidneys, and lungs, where it plays a protective role against oxidative stress and aldehyde-induced cellular damage. ALDH3B1 contributes to cellular homeostasis by metabolizing toxic aldehydes such as formaldehyde and 4-HNE, reducing protein and DNA adduct formation. Dysregulation of ALDH3B1 has been linked to metabolic and neurodegenerative disorders, where impaired aldehyde detoxification exacerbates oxidative damage. In cancer, ALDH3B1 has been identified as a tumor suppressor in certain contexts, as its activity reduces cellular oxidative stress and inhibits tumor progression. Recent studies suggest its involvement in maintaining redox balance and preventing aldehyde-associated toxicity in tissues exposed to oxidative or environmental stressors.
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